Table 5.
Average causal mediation effect through IDF on survival to hospital discharge of positive chest X-ray, central venous catheter, and endotracheal intubation.
| Variables |
Indirect effect (ACME, 95% CI) |
Direct effect (ADE, 95% CI) |
Total effect (95% CI) |
Proportion mediated (95% CI) |
|---|---|---|---|---|
| Positive chest X-ray | −0.01 (−0.03 to 0.00) | −0.06 (−0.13 to 0.00) | −0.07(-0.14 to −0.01) | 0.19 (0.02 to 1.14), P = 0.04 |
| Central venous catheter | −0.01 (−0.03 to 0.00) | −0.09(−0.16 to −0.01) | −0.10(−0.17 to −0.02) | 0.10 (0.01 to 0.52), P = 0.02 |
| Endotracheal intubation | 0.01 (0.00 to 0.02) | −0.16(−0.22 to −0.09) | −0.15(−0.22 to −0.08) | −0.06 (−0.20 to 0.00), P = 0.06 |
Total effect: the sum of the direct and indirect effects. Proportion mediated: the coefficient of the indirect and total effects. ACME, average causal mediation effect; ADE, average direct effect; IDF, incidence density of fever.