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The anatomy of the nail unit. a Fat: loculated by fibrous septae, Pacinian corpuscles: rapidly adapting mechanoreceptors, respond to sudden changes in vibration/pressure. Ruffini corpuscles: slowly adapting mechanoreceptors, respond to stretch, proprioception, mechanical deformation within joints, located superficially. b Schematic demonstration of pain in glomus tumor. c The mechanism of bone pain in enchondroma, inclusion cyst, and keratoacanthoma.
