Table 6.
Inhibition of α-amylase activity by Carica papaya seed extracts (% Inhibition).
Concentration | n-hexane | Ethylacetate | Methanol | Aqueous | Acarbose (standard) |
---|---|---|---|---|---|
20 | 23.04 ± 1.82a | 22.52 ± 6.06 | 21.86 ± 0.72 | 18.52 ± 0.76 | 23.63 ± 0.33 |
40 | 37.37 ± 2.33ab | 33.61 ± 1.56b | 26.47 ± 4.73 | 21.43 ± 2.58 | 31.39 ± 1.65 |
60 | 48.66 ± 1.79ab | 38.26 ± 3.18 | 26.41 ± 2.45 | 23.20 ± 1.01 | 42.49 ± 4.63 |
80 | 51.15 ± 3.71a | 49.85 ± 5.92 | 41.53 ± 6.40 | 44.37 ± 1.77 | 57.38 ± 1.62 |
100 | 53.27 ± 0.10 | 58.12 ± 0.18a | 52.22 ± 7.90 | 56.25 ± 1.87 | 58.69 ± 4.10 |
IC50 (mg/ml) | 76.96 | 79.18 | 94.63 | 93.26 | 74.64 |
Values are Mean ± SD (n = 3).
Significantly (p < 0.05) higher compared to other extracts at the same concentration.
Significantly (p < 0.05) higher compared to Acarbose at the same concentration.