Table 7.
Inhibition of α-glucosidase activity by Carica papaya seed extracts (% Inhibition).
| Concentration | n-hexane | Ethyl acetate | Methanol | Aqueous | Acarbose (standard) |
|---|---|---|---|---|---|
| 20 | 20.09 ± 0.79 | 20.79 ± 6.97 | 24.31 ± 2.25a | 19.03 ± 2.74 | 25.87 ± 2.04 |
| 40 | 23.64 ± 1.12 | 30.20 ± 1.92 | 35.57 ± 1.72a | 26.12 ± 1.91 | 37.64 ± 0.88 |
| 60 | 33.27 ± 0.79 | 31.56 ± 4.25 | 41.80 ± 2.37a | 34.48 ± 0.63 | 46.71 ± 13.56 |
| 80 | 58.60 ± 0.95ab | 55.80 ± 1.96 | 43.48 ± 1.25 | 38.76 ± 1.19 | 54.09 ± 1.61 |
| 100 | 64.84 ± 1.10ab | 62.28 ± 1.19 | 59.67 ± 1.89 | 41.48 ± 14.85 | 62.38 ± 3.47 |
| IC50 (mg/ml) | 75.78 | 77.41 | 79.35 | 102.40 | 71.47 |
Values are Mean ± SD (n = 3).
a
Significantly (p < 0.05) higher compared to other extracts at the same concentration.
b
Significantly (p < 0.05) higher compared to Acarbose at the same concentration.