Skin anti-aging of the upper and of the lower face: treatment of forehead wrinkles with botulinum toxin (a, b), before (a) and after (b) treatment, and treatment of perioral wrinkles (c, d) with injectable hyaluronic acid, before (c) and after (d) treatment (courtesy of Monika Hess, MD, Zürich, Switzerland; courtesy of Monika Hess, MD, Zürich, Switzerland).