Table 2.
Immunological laboratory findings of patients with 22q11.2PDS and 22q11.2DDS
| 22q11.2 proximal deletion syndrome | 22q11.2 distal deletion syndrome | |
|---|---|---|
| Leukocytes, cells/µL | 10,340 (4,500 – 10,000) | 4,200 (4,500 – 10,000) |
| CD3+, cells/µL | 1,018 (959 – 2,577) | 473 (959 – 2,577) |
| CD4+, cells/µL | 533 (544 – 1,663) | 271 (544 – 1,663) |
| CD8+, cells/µL | 270 (272 – 932) | 164 (272 – 932) |
| IgA, mg/dL | <1 (70 –320) | 830 (70 – 400) |
| IgM, mg/dL | 82 (50 – 240) | 154.3 (40 – 230) |
| IgG, mg/dL | 840 (640 – 1,350) | 1,212.8 (700 – 1,600) |
| IgE, mg/dL | ND | 2.3 (0 – 100) |
| IgD, mg/dL | ND | 44.8 (0 – 152.7) |
Absolute numbers of leukocytes and CD3+, CD4+ and CD8+ T cell are shown with reference values in parentheses. Serum immunoglobulin levels are shown with reference values in parentheses. For the patient with 22q11.2PDS, serum Ig levels are secondary to treatment with exogenous immunoglobulin. ND, not done.