Table 1.
Clinical features and staging of patients with lacrimal sac mucoepidermoid carcinoma
Patient | Age, years/sex | Laterality | Presenting symptoms (duration in months) | Imaging findings (CT scan) | Secondary sites of involvementa | pTb | cNb | cMb | Stageb | Surgical management | Adjuvant therapy | Recurrence or metastases, follow-up in months | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 45/M | Left | Epiphora and recurrent dacryocystitis (12 months) | 2.5-cm soft tissue mass at medial canthal area, associated with globe displacement | Inferomedial orbit, nasal cavity, ethmoid sinus | 3 | x | x | At least III | LS and NLD resection, lateral rhinotomy, ethmoidectomy, medial maxillectomy, orbital exenteration | XRT | N/A | |
2 | 24/M | Right | Ephiphora (9 months), LS mass (4 months) | N/A | Nasal cavity, medial orbit | 3 | x | x | At least III | LS and NLD resection, medial orbital tissue resection | None | N/A | |
3 | 62/M | Right | Epiphora, recurrent dacyocystitis, LS mass, pain (16 months) | 1.9-cm LS mass with erosion of lacrimal bone and bony lacrimal duct | Maxilla, medial orbit | 3 | 0 | 0 | III | LS and NLD resection, ethmoidectomy, medial maxillectomy, middle and inferior turbinectomy | None | No, 23 months | |
4 | 66/F | Left | Epiphora, LS mass, eye irritation, nasal congestion (10 months) | 1.6-cm soft tissue mass in LS without bony erosion | Nasal cavity | 1 | 0 | 0 | I | LS and NLD resection, medial maxillectomy, ethmoidectomy, anterior turbinectomy | XRT | No, 20 months | |
5 | 65/M | Right | Epiphora, eye pain (6 months) | 2.5-cm soft tissue mass in LS | Maxilla, medial orbit | 3 | 0 | 0 | III | LS and NLD resection, medial maxillectomy | XRT | No, 13 months | |
6 | 63/M | Right | LS mass, pain (6 months) | 1.5-cm soft tissue mass in LS with bony changes | Maxilla, medial orbit | 3 | 0 | 0 | III | LS resection, medial maxillectomy | XRT | No, 17 months |
CT, computed tomography; NLD, nasolacrimal duct; LS, lacrimal sac; x, not available; N/A, not available; pT, pathology tumor grouping by size; cN, clinical documentation of nodal metastasis; cM, clinical documentation of distal metastasis; XRT, external beam radiotherapy.
Based on imaging studies with pathologic confirmation.
TNM classification and stage groupings are adopted from the AJCC classification of carcinoma of the nasal cavity and ethmoid sinus (patients 1, 2, and 4) and maxillary sinus (patients 3, 5, and 6), 8th edition [18].