TABLE 3.

Comparison of our microfluidic devices with those of previous studies.

	Neuron device	Modified boyden	Nerve organoid device
Company	Xona Microfluidics	Corning	Jiksak Bioengineering
Dimension	2 D	2 D	3 D (axon bundle)
Cell type	Primary mouse motor neuron	Primary mouse motor neuron	iPSCs derived motor neuron
Pore size	1∼3 um	3 um	150∼200 um
Axon length	150 um	NA	10,000 μm (1 cm)
Retrievable neurons	∼10*3	5 × 10*5	10*4-
RNA	20 pg-	0.3 ng/μl	12 ng (l ng/μl) -
References	Briese et al., 2016; Bigler et al., 2017; Nijssen et al., 2018, etc.	Rotem et al., 2017; Maciel et al., 2018, etc.	Akiyama et al., 2019; Kawada et al., 2017