Table 4.
Effect of RS and CA extracts on study parameters.
Groups | Insulin (μg/L) | HOMA-IR | Creatinine (mg/dL) | Relative Organ Weight, % |
||
---|---|---|---|---|---|---|
Heart | Spleen | Kidney | ||||
NPD | 2.26 ± 0.10 | 9.10 ± 0.52 | 0.72 ± 0.02 | 0.29 ± 0.04 | 0.19 ± 0.01 | 0.32 ± 0.04 |
NPD + STZ | 2.12 ± 0.17 | 9.10 ± 0.79 | 0.78 ± 0.07 | 0.29 ± 0.01 | 0.14 ± 0.01 | 0.34 ± 0.01 |
HFD + STZ | 1.57 ± 0.09y | 28.00 ± 0.89z | 0.87 ± 0.05 | 0.28 ± 0.03 | 0.12 ± 0.03 | 0.44 ± 0.03 |
RS4 | 2.26 ± 0.12a | 19.70 ± 3.81 | 0.81 ± 0.04 | 0.31 ± 0.01 | 0.15 ± 0.01 | 0.34 ± 0.01 |
RS8 | 2.40 ± 0.13b | 15.50 ± 3.07b | 0.94 ± 0.03 | 0.33 ± 0.01 | 0.16 ± 0.01 | 0.35 ± 0.01 |
CA4 | 1.69 ± 0.14 | 18.60 ± 2.32 | 0.82 ± 0.04 | 0.37 ± 0.01 | 0.18 ± 0.01 | 0.36 ± 0.01 |
CA8 | 1.85 ± 0.08 | 10.40 ± 1.22c | 0.92 ± 0.07 | 0.31 ± 0.01 | 0.16 ± 0.01 | 0.41 ± 0.04 |
MET | 1.73 ± 0.16 | 10.50 ± 1.57c | 0.81 ± 0.04 | 0.30 ± 0.04 | 0.13 ± 0.02 | 0.35 ± 0.04 |
Values are expressed as Mean ± SEM (n = 6), analyzed by one way ANOVA followed by Bonferroni test. y denotes p < 0.01 & z denotes p < 0.001 as compared to NPD, a denotes p < 0.05, b denotes p < 0.01 & c denotes p < 0.001 as compared to HFD + STZ.