Table 5.

Adjusted Cox proportional hazard model analyseswith 95% confidence interval for asthma hospitalization in children with asthma.

Variables	Adjusted Hazard Ratioa	95% Confidence Interval	p – Value
Gender
Males	reference
Females	0.90	0.84–0.96
Age at diagnosis
0–5 years	reference
6–18 years	0.66	0.59–0.74	<0.0001
Total number of comorbiditiesb
1	reference
2	0.98	0.13–7.49
3	1.30	0.18–9.29
4	1.29	0.18–9.19
≧5	1.45	0.20–10.35
Total number of asthma medicationc
1	reference
2	1.70	1.04–2.77	0.0352
3	3.32	2.10–5.27	<0.0001
4	5.05	3.20–7.95	<0.0001
≧5	10.37	6.57–16.35	<0.0001
CHM usage
No(＜30 days)	reference
Yes(≧30 days)	0.90	0.83–0.95	0.0048

Abbreviations: CHM, Chinese herbal medicine.

^aadjusting all listed variables.

^bComorbidities including:allergic rhinitis, acute upper respiratory infection, acute bronchitis, acute sinusitis, atopicdermatitis, gastroesophageal reflux disease, urticaria.

^cAsthma medication including:short-acting β2 agonists, short-acting anticholinergics, inhaled glucocorticosteroids,long-acting β2 agonists, antileukotriene, mast-cell stabilizers, anti-IgE monoclonal antibody.