Table 4.
Hematological values for ICR mice in 24-week feed study of B. pilosa.
| Parameter | Unit | Males |
Females |
References25 range of 20–24 week ICR mice |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0% BP | 0.5% BP | 2.5% BP | 5% BP | 10% BP | 0% BP | 0.5% BP | 2.5% BP | 5% BP | 10% BP | Male | Female | ||
| RBC | 1012/L | 9.52 ± 0.61 | 9.68 ± 0.65 | 9.33 ± 0.61 | 9.52 ± 0.39 | 9.85 ± 0.79 | 9.71 ± 0.39 | 9.88 ± 0.73 | 9.98 ± 0.31 | 9.65 ± 0.44 | 9.98 ± 0.93 | 9.02–10.42 | 9.74–10.32 |
| WBC | 109/L | 9.88 ± 1.18 | 10.15 ± 2.32 | 9.71 ± 0.66 | 9.26 ± 0.83 | 9.53 ± 1.06 | 9.12 ± 1.74 | 9.25 ± 1.16 | 9.22 ± 0.62 | 9.55 ± 0.73 | 9.72 ± 1.14 | 9.13–14.71 | 8.87–14.69 |
| HGB | g/dL | 13.5 ± 1.6 | 14.3 ± 0.8 | 14.9 ± 1.4 | 16.1 ± 1.1 | 14.5 ± 0.6 | 14.8 ± 0.3 | 14.9 ± 0.2 | 14.5 ± 0.7 | 14.2 ± 1.2 | 15.0 ± 0.8 | 13.5–17.2 | 14.4–15.8 |
| HCT | % | 51.2 ± 2.1 | 53.0 ± 1.4 | 49.8 ± 3.0 | 52.9 ± 1.3 | 51.7 ± 2.5 | 52.1 ± 1.8 | 52.2 ± 0.9 | 51.1 ± 1.7 | 50.0 ± 1.7 | 51.8 ± 1.6 | 49.4–55.6 | 49.0–56.9 |
| MCV | fL | 55.5 ± 2.5 | 56.4 ± 3.2 | 55.5 ± 1.5 | 56.0 ± 2.7 | 56.1 ± 2.7 | 54.3 ± 0.8 | 55.8 ± 2.9 | 56.4 ± 2.9 | 54.7 ± 1.6 | 55.2 ± 2.4 | 49.9–56.5 | 49.0–57.9 |
| MCH | pg | 15.6 ± 0.6 | 15.7 ± 0.9 | 15.6 ± 0.4 | 16.2 ± 1.3 | 16.2 ± 1.7 | 16.5 ± 0.7 | 15.5 ± 0.6 | 15.8 ± 0.8 | 16.1 ± 0.8 | 16.3 ± 0.9 | 14.5–16.9 | 14.7–16.5 |
| Plates | 1010/L | 129.9 ± 16.1 | 104.6 ± 4.3 | 102.6 ± 14.8 | 119.8 ± 15.1 | 118.2 ± 16.1 | 109.2 ± 11.9 | 108.1 ± 6.9 | 111.0 ± 11.7 | 115.2 ± 4.3 | 112.1 ± 13.7 | 99.38–144.3 | 109.9–148.7 |
| Lymphocytes | % | 80.0 ± 4.1 | 76.6 ± 9.3 | 75.3 ± 5.7 | 70.2 ± 8.7 | 77.9 ± 5.8 | 78.2 ± 4.9 | 77.9 ± 5.3 | 74.4 ± 4.9 | 73.5 ± 8.9 | 75.3 ± 4.7 | 63.9–90.2 | 74.8–82.8 |
| Monocytes | % | 3.7 ± 0.8 | 4.1 ± 1.1 | 5.2 ± 1.2 | 4.5 ± 1.7 | 4.9 ± 1.3 | 4.1 ± 0.9 | 3.5 ± 0.8 | 6.4 ± 1.8 | 4.3 ± 0.8 | 4.9 ± 1.1 | 3.2–6.4 | 2.1–7.1 |
| Eosinophils | % | 1.2 ± 0.3 | 1.3 ± 0.2 | 1.3 ± 0.7 | 0.8 ± 1.3 | 1.8 ± 1.3 | 0.7 ± 0.1 | 1.0 ± 0.4 | 1.2 ± 0.6 | 1.9 ± 0.7 | 1.7 ± 1.3 | 0.8–3.1 | 0.1–5.1 |
| Neutrophils | % | 16.3 ± 4.4 | 13.3 ± 3.1 | 16.7 ± 5.2 | 18.1 ± 6.4 | 16.5 ± 5.4 | 13.7 ± 1.1 | 15.7 ± 2.6 | 15.3 ± 5.5 | 19.3 ± 5.8 | 14.7 ± 2.8 | 2.1–27.3 | 9.1–19.3 |
Blood samples of both sexes of mice from Fig. 1 were analyzed after 24-week treatment. The data are expressed as mean ± SEM of hematological values. Statistical comparisons of control mice (0% BP) and BP-fed mice were performed by one-way ANOVA plus the Tukey multiple range test and no statistical difference between treatment and control groups was observed. Abbreviations: WBC, white blood count; RBC, red blood cell; HGB, hemoglobin; MCV, mean corpuscular volume; and MCH, mean corpuscular hemoglobin.