Figure 1.

Clinical, radiographic, and microscopic photographs of case 8, a primary hepatocellular carcinoma with metastasis to the gingiva. (A) An exophytic, partially ulcerated mass at the buccal gingiva of teeth 43 to 45. (B) Panoramic radiography revealed no bony destruction at the mandibular body between teeth 43 and 45. (C) The metastatic carcinoma composed of islands of hyperchromatic and pleomorphic tumor cells (hematoxylin and eosin stain; magnification, 200×). (D, E and F) The tumor cells were positive for CK7 (D, magnification, 100×), negative for CK20 (E, magnification, 100×), and positive for HepaPar1 (F, magnification, 100×). (G) Microscopic features of the gingival metastatic lesion are consistent with a primary hepatocellular carcinoma (magnification, 100×).