Table 2.
Comparisons of frequencies of microcytosis (mean corpuscular volume or MCV < 80 fL), macrocytosis (MCV ≥ 100 fL), blood hemoglobin (Hb) and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody (GPCA) positivity between 143 burning mouth syndrome (BMS) patients with iron deficiency (ID/BMS patients) and 442 healthy control subjects.
| Group | Patient number (%) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Microcytosis (MCV < 80 fL) | Macrocytosis (MCV ≥ 100 fL) | Hb deficiency (Men < 13 g/dL, women < 12 g/dL) | Iron deficiency (<60 μg/dL) | Vitamin B12 deficiency (<200 pg/mL) | Folic acid deficiency (<4 ng/mL) | Hyperhomocysteinemia (>12.3 μM) | GPCA positivity | |
| ID/BMS patients (n = 143) | 30 (21.0) | 11 (7.7) | 80 (55.9) | 143 (100.0) | 11 (7.7) | 3 (2.1) | 39 (27.3) | 18 (12.6) |
| aP-value | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| Healthy control subjects (n = 442) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 11 (2.5) | 8 (1.8) |
a
Comparisons of frequencies of parameters between 143 ID/BMS patients and 442 healthy control subjects by chi-square test.