Table 1.
Expression of nucleotide-binding oligomerization domain (NOD) 1 and NOD2 in normal oral mucosa (NOM) and oral lichen planus (OLP).
| NOM group | % of positive cells | OLP group | % of positive cells | |||
|---|---|---|---|---|---|---|
| NOD1 | Spinous and superfical layer | 44.0 ± 16.0 | ++ | Spinous and keratinized layer | 62.4 ± 12.8 | +++ |
| Basal and parabasal layer | 8.2 ± 4.7 | + | Basal and parabasal layer | 12 ± 5.7 | ++ | |
| Lymphocytes | 0.0 ± 0.0 | – | Lymphocytes | 0.0 ± 0.0 | – | |
| NOD2 | Spinous and superfical layer | 0.0 ± 0.0 | – | Spinous and keratinized layer | 0.0 ± 0.0 | – |
| Basal and parabasal layer | 0.0 ± 0.0 | – | Basal and parabasal layer | 7.9 ± 3.1* | + | |
| Lymphocytes | 0.0 ± 0.0 | – | Lymphocytes | 84.2 ± 6.6*** | +++ | |
−; negative (0), +; mild (<10%), ++; moderate (10%–50%), +++; strong (>50%).
Significant comparison of NOM and OLP (*, P < 0.05; ***, P < 0.001, Mann–Whitney U test).