Figure 2.

Oral treatment with the herbal formula B307 (CHM) effectively alleviated hypothyroidism-induced abnormal increases in thyroid-stimulating hormone (TSH) in the serum. (a) Statistical comparison of quantified level of serum TSH among sham, CHM, TD, and TD + CHM rats. Levels of serum TSH in TD rats were significantly higher than those in sham, CHM, and TD + CHM rats. (b and c) Statistical comparison of quantified levels of the serum T3 and T4 among sham, CHM, TD, and TD + CHM rats. Levels of serum T3 and T4 of TD and TD + CHM rats were significantly lower than in sham and CHM rats. The results are shown as mean ± SEM (^∗∗P < 0.01, n = 5 for each group, two-way ANOVA followed by Student–Newman–Keuls multiple comparison posttest).