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Inhibition of UBA1 decreased cellular oxidative stress in diet-induced atherosclerosis in Apoe-/- mice. (a) Quantitative real-time PCR analysis of aortic expression of NADPH oxidases (Nox1, Nox2, and Nox4). (b) DHE staining and quantitation of the lesional oxidative stress level in the aortic root. n = 5 per group; ∗: <0.05.
