Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of selected teicoplanin aglycone analogues on the replication of HCV replicons
| Huh Mono |
Huh 9-13 |
|||
|---|---|---|---|---|
| LCTA | EC50 | CC50 | EC50 | CC50 |
| 563 | 5.1 ± 0.7 | >60 | 15 ± 2.6 | >60 |
| 877 | 14 ± 2.6 | >60 | 10 ± 8.9 | >60 |
| 901 | 29 ± 1.0 | >60 | 54 ± 12 | >60 |
| 914 | 4.8 ± 2.1 | >60 | 17 ± 2.2 | >60 |
| 949 | 6.9 ± 2.1 | >60 | 3.9 ± 0.9 | >60 |
| VX-950 | 1.0 ± 0.3 | >33 | 0.4 ± 0.1 | 24 ± 4 |
Data are expressed in μM and are means ± SD for three or four independent experiments.
The NS3 protease inhibitor (VX-950) is given as a reference HCV inhibitor.
