Table 2.
Huh 5-2 |
HCVcc |
|||
---|---|---|---|---|
LCTA | EC50 | CC50 | EC50 | CC50 |
949 | 4.9 ± 0.9 | >60 | 5.2 ± 0.1 | >60 |
1701 | 15 ± 2.8 | 60 | >10 | >60 |
1703 | 5.7 ± 0.5 | >60 | 4.6 ± 3.7 | >60 |
1704 | 3.6 ± 1.2 | >60 | 3.4 ± 2.2 | >60 |
1705 | 2.9 ± 0.7 | >60 | >10 | >60 |
1706 | 11 ± 1.2 | >60 | >10 | >60 |
1707 | 7 ± 0.1 | >60 | 3.5 ± 0.5 | >60 |
VX-950 | 1.0 ± 0.7 | >33 | 0.2 ± 0.1 | >10 |
HCVcc, infectious HCV in cell culture system.
Data are expressed in μM and are means ± SD for three to four independent experiments.