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. 2004 Dec 27;17(2):167–176. doi: 10.1093/intimm/dxh197

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© 2004 The Japanese Society for Immunology

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Fig. 3. — T cell responses in patients vaccinated with TA-HPV. Responses against HPV peptide pools were measured pre- and post-vaccination (at least three time points) in nine patients with HPV-associated LGTN (VAC001–003, VAC005, VAC006 and VAC008–011). For each patient, cryopreserved PBMC from multiple time points were tested in the same experiment to minimise variability. Responses marked with asterisk represent significant post-vaccine T cell responses (>2SD of pre-vaccine response). Note that VAC002 produced a mean of 303 spots for day 61 and a mean of 340 spots for day 91. For the majority of patients, PPP responses exceeded 200 spots per well and were not precisely counted above this number.