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. 2016 Mar 19;145(4):486–496. doi: 10.1093/ajcp/aqw021

Image 5.

Image 5

Image 5

Focus of endometrial adenocarcinoma, endometrioid type, deemed equivocal for myometrial invasion, ×50 (A, C, and E) and ×160 (B, D, and F). A and B, Adenocarcinoma has an expansile growth pattern; borders are smooth and noninfiltrative, but definitive endometrial-type stroma is not visualized (H&E). C and D, Mesenchyma around malignant glands shows moderate interferon-induced transmembrane protein 1 staining, in keeping with an endometrial stromal phenotype (hence favoring adenomyosis involvement and excluding myoinvasion). E, and F, Peritumoral mesenchyma is also strongly positive for CD10.