Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Jan 1;254(2):232–239. doi: 10.1111/j.1574-6968.2005.00031.x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2005 Federation of European Microbiological Societies

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

Schematic representation of the DnaA protein and primer design for the amplification of the partial mycobacterial dnaA gene. Number indicates the nucleotide position of Mycobacterium tuberculosis, GenBank accession number AL021427. (a) The DnaA protein from M. tuberculosis contains four domains. Domain 1 is involved in interaction with DnaB. Domain 2 constitutes a flexible loop. DNA unwinding required Domain 3. Domain 4 is sufficient for specific binding to DNA. Primers U1F and U1R were used to generate about 400 bp fragment from dnaA of 27 mycobacterial spp. (b) Analysis and comparison region used in this study are indicated by a bar (298–508 bp).