Fig. 2.

Analysis of protein-protein interactions of human virus receptors. (A) Comparison of the degree of proteins between human viral receptors, human cell membrane proteins, human membrane proteins and all human proteins in the human PPIN which were derived from Menche's work and included 13460 human proteins and 141296 interactions. For clarity, the node degree was transformed in natural logarithm. “***”, p-value < 0.001. (B) A partial human PPI network derived from Menche's work. It was only composed of the PPIs which involved at least one viral receptor protein (in triangle), and it included 1475 human proteins (67 virus receptors (in triangle) and 1408 other proteins (in circle)) and 2280 PPIs (edges in gray)