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. 2012 Aug;90(8):2784–2793. doi: 10.2527/jas.2011-4518

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Figure 5. — (A) Serum IL-10 and (B) Haptoglobin (Hp) concentrations in pigs fed control or mannan oligosaccharide (Actigen; ACT, Alltech, Inc., Nicholasville, KY) diets with or without porcine reproductive and respiratory syndrome virus (PRRSV) infection. Infection with PRRSV increased the serum concentrations of IL-10 and Hp in infected pigs (P < 0.001). The ACT × PRRSV interaction tended to be significant for IL-10 (P = 0.088), but was significant for Hp (P = 0.047). There were also significant effects of day or interaction of day × PRRSV on IL-10 and Hp (P < 0.001). Values were means; pooled SEM were 4.7 pg/mL and 142.5 μg/mL for IL-10 and Hp, respectively. A pig was an experimental unit; each treatment had 8 pigs except ICON (7 pigs, 1 pig euthanized at 18 d postinfection). CON: uninfected control-fed pigs; ACT: uninfected ACT-fed pigs; ICON: infected control-fed pigs; IACT: infected ACT-fed pigs. †P < 0.1; *P < 0.05; ***P < 0.001.