Table.
Selected viral pathogens of the respiratory tract, approved therapy and key antiviral agents undergoing clinical trials or with evidence of clinical activity
| Causative virus | Currently approved therapya | Agents under clinical investigation or used empirically |
|---|---|---|
| aLicensed in North America and/or EU countries. | ||
| bProphylaxis only. | ||
| Rhinovirus | – | t-ICAMs (tremacamra, BAY z 9700) |
| pleconaril | ||
| AG-7088 | ||
| Influenza A virus | amantadine, rimantadine | |
| Influenza A + B virus | zanamivir, oseltamivir, ribavirin | RWJ-270201 |
| Respiratory syncytial virus | ribavirin | |
| palivizumabb | ||
| Parainfluenza virus | – | ribavirin |
| Adenovirus | – | ribavirin |
| Papillomavirus (recurrent respiratory papillomatosis) | – | α-interferon |
| cidofovir | ||
| Hantavirus | – | ribavirin |
| Cytomegalovirus | ganciclovir | cidofovir |
| immune globulin | foscarnet | |
| Herpes simplex virus | acyclovir | famciclovir |
| valaciclovir | ||
| Varicella-zoster virus | acyclovir | famciclovir |
| valaciclovir | ||