Table 4.
Medications used on admission and during hospitalization
Drugs | Medications on admission |
Medications during hospitalization |
||||||
---|---|---|---|---|---|---|---|---|
All patients | AKI | Non-AKI | P value | All patients | AKI | Non-AKI | P value | |
RAAS inhibitors | 33 of 701 (4.7) | 0 of 36 (0.0) | 33 of 665 (5.0) | 0.334 | 41 of 701 (5.8) | 0 of 36 (0.0) | 41 of 665 (6.2) | 0.242 |
Antibiotics | 498 of 701 (71.0) | 27 of 36 (75.0) | 471 of 665 (70.8) | 0.591 | 600 of 701 (85.6) | 35 of 36 (97.2) | 565 of 665 (85.0) | 0.041 |
Antivirals | 512 of 701 (73.0) | 21 of 36 (58.3) | 491 of 665 (73.8) | 0.041 | 658 of 701 (93.9) | 32 of 36 (88.9) | 626 of 665 (94.1) | 0.357 |
Umifenovir | 343 of 701 (48.9) | 14 of 36 (38.9) | 329 of 665 (49.5) | 0.216 | 475 of 701 (67.8) | 17 of 36 (47.2) | 458 of 665 (68.9) | 0.007 |
Ganciclovir | 24 of 701 (3.4) | 0 of 36 (0.0) | 24 of 665 (3.6) | 0.491 | 27 of 701 (3.9) | 0 of 36 (0.0) | 27 of 665 (4.1) | 0.430 |
Interferon | 129 of 701 (18.4) | 6 of 36 (16.7) | 123 of 665 (18.5) | 0.783 | 169 of 701 (24.1) | 9 of 36 (25.0) | 160 of 665 (24.1) | 0.898 |
Lopinavir and ritonavir | 74 of 701 (10.6) | 2 of 36 (5.6) | 72 of 665 (10.8) | 0.469 | 196 of 701 (28.0) | 4 of 36 (11.1) | 192 of 665 (28.9) | 0.021 |
Oseltamivir | 39 of 701 (5.6) | 1 of 36 (2.8) | 38 of 665 (5.7) | 0.707 | 79 of 701 (11.3) | 1 of 36 (2.8) | 78 of 665 (11.7) | 0.166 |
Ribavirin | 8 of 701 (1.1) | 0 of 36 (0.0) | 8 of 665 (1.2) | 1.000 | 33 of 701 (4.7) | 0 of 36 (0.0) | 33 of 665 (5.0) | 0.334 |
Antidiabetic | 68 of 701 (9.7) | 3 of 36 (8.3) | 65 of 665 (9.8) | 1.000 | 119 of 701 (17.0) | 4 of 36 (11.1) | 115 of 665 (17.3) | 0.336 |
Diuretics | 10 of 701 (1.4) | 1 of 36 (2.8) | 9 of 665 (1.4) | 0.412 | 67 of 701 (9.6) | 26 of 36 (72.2) | 41 of 665 (6.2) | <0.001 |
Glucocorticoids | 259 of 701 (36.9) | 21 of 36 (58.3) | 238 of 665 (35.8) | 0.006 | 387 of 701 (55.2) | 22 of 36 (61.1) | 365 of 665 (54.9) | 0.465 |
AKI, acute kidney injury; RAAS, renin-angiotensin-aldosterone system.
RAAS inhibitors include angiotensin-converting-enzyme inhibitor and angiotensin receptor blocker.