Table 1.
Functions of NOS in DV infection
| Types of NOS | Location | Cell | Regulation | Dengue disease | |
|---|---|---|---|---|---|
| Lesions | * References | ||||
| Neuronal NOS (nNOS or NOS1) | Brain | Microglia | Ca2+/CAM | Blood–brain barrier damage | 1991, 2008 |
| Inducible NOS (iNOS or NOS2) | Immune system, cardiovascular system | Macrophage, dendritic cell | Ca2+ independent | Virus replication inhibited | 2005, 2006 |
| Endothelial NOS (eNOS or NOS3) | Endothelium | Endothelial cells | Ca2+/CAM | Increased capillary permeability | 2008, 1994, 1990 |
*
Only selected references have been cited.