Table 3:

Associations of PWV measures, derived CAVI, and derived CFVI with the risk of all-cause mortality

Characteristics		Q1		Q2	Q3		Q4
		HR (95% CI)	P*		HR (95% CI)	P*	HR (95% CI)	P*
Central arterial stiffness
cfPWV	Model 1	1.01 (0.65, 1.57)	0.96	ref	1.76 (1.19, 2.62)	0.01	1.55 (1.04, 2.32)	0.03
	Model 2	1.11 (0.71, 1.73)	0.65	ref	1.60 (1.08, 2.39)	0.02	1.24 (0.82, 1.87)	0.30
	Model 3	1.13 (0.72, 1.76)	0.59	ref	1.55 (1.04, 2.32)	0.03	1.13 (0.74, 1.72)	0.57
	Model 4	1.07 (0.69, 1.68)	0.75	ref	1.44 (0.96, 2.15)	0.07	0.99 (0.65, 1.51)	0.96
hfPWV	Model 1	1.08 (0.71, 1.66)	0.71	ref	1.39 (0.92, 2.09)	0.11	1.71 (1.15, 2.53)	0.01
	Model 2	1.21 (0.79, 1.86)	0.39	ref	1.26 (0.84, 1.90)	0.27	1.38 (0.92, 2.06)	0.12
	Model 3	1.28 (0.83, 1.96)	0.27	ref	1.21 (0.80, 1.82)	0.37	1.21 (0.80, 1.83)	0.37
	Model 4	1.25 (0.81, 1.93)	0.31	ref	1.19 (0.79, 1.80)	0.40	1.02 (0.67, 1.55)	0.94
Derived CFVI	Model 1	1.24 (0.80, 1.93)	0.33	ref	1.51 (0.99, 2.30)	0.06	2.03 (1.36, 3.03)	0.001
	Model 2	1.31 (0.85, 2.04)	0.22	ref	1.30 (0.85, 2.00)	0.22	1.56 (1.03, 2.36)	0.04
	Model 3	1.42 (0.92, 2.21)	0.12	ref	1.26 (0.82, 1.93)	0.29	1.40 (0.92, 2.14)	0.11
	Model 4	1.40 (0.90, 2.18)	0.13	ref	1.24 (0.81, 1.90)	0.32	1.23 (0.81, 1.89)	0.33
Composite arterial stiffness
baPWV	Model 1	0.92 (0.62, 1.37)	0.69	ref	1.08 (0.73, 1.59)	0.69	1.65 (1.16, 2.35)	0.01
	Model 2	1.06 (0.71, 1.59)	0.76	ref	0.99 (0.67, 1.45)	0.95	1.33 (0.93, 1.90)	0.12
	Model 3	1.06 (0.70, 1.59)	0.78	ref	0.98 (0.66, 1.45)	0.91	1.27 (0.87, 1.85)	0.21
	Model 4	1.02 (0.68, 1.54)	0.92	ref	0.99 (0.67, 1.46)	0.95	1.28 (0.88, 1.86)	0.21
haPWV	Model 1	1.06 (0.70, 1.60)	0.79	ref	1.02 (0.67, 1.55)	0.93	1.59 (1.08, 2.34)	0.02
	Model 2	1.18 (0.78, 1.79)	0.44	ref	0.94 (0.61, 1.43)	0.76	1.25 (0.85, 1.85)	0.26
	Model 3	1.26 (0.83, 1.92)	0.29	ref	0.88 (0.58, 1.35)	0.57	1.07 (0.71, 1.61)	0.74
	Model 4	1.22 (0.80, 1.86)	0.36	ref	0.87 (0.57, 1.33)	0.51	1.06 (0.70, 1.60)	0.79
Derived CAVI	Model 1	1.30 (0.84, 2.03)	0.24	ref	1.63 (1.07, 2.49)	0.02	1.98 (1.32, 2.99)	0.001
	Model 2	1.37 (0.88, 2.14)	0.16	ref	1.39 (0.91, 2.13)	0.13	1.42 (0.93, 2.16)	0.11
	Model 3	1.54 (0.99, 2.41)	0.06	ref	1.37 (0.89, 2.10)	0.15	1.24 (0.81, 1.91)	0.32
	Model 4	1.45 (0.93, 2.27)	0.11	ref	1.34 (0.87, 2.06)	0.18	1.25 (0.81, 1.92)	0.32

Model 1: Crude

Model 2: Age, sex, race

Model 3: Model 2 + education, current smoking, body mass index, history of diabetes, mean arterial pressure, antihypertensive medication, total cholesterol, high-density lipoprotein

Model 4: Model 3 + ankle brachial index, estimated glomerular filtration rate, albumin-creatinine ratio

HR=hazard ratio; Q1, Q2, Q3, Q4=quartile 1, quartile 2, quartile 3, quartile 4

^*P-values test quartile-specific estimates vs. the referent (quartile 2)