Figure 1. Single injection of MDPV affects dopamine-related gene expression in the NAc, VTA and PFC regions of rat’s brain.
qRT-PCR quantification of the mRNA levels for DRD1 (A), DRD2 (B), DAT1 (C) and VMAT2 (D), genes in brain tissue obtained from rats treated with single injection of MDPV (1 mg/kg) (brains extracted 120 min after last MDPV injection). Gene expression level in control group was set as 1. Data are presented as fold-change in gene expression normalized to GAPDH, represented as ±SEM. N=4–6. *p < 0.05 or **p < 0.01 versus saline control (MDPV 0 mg/kg).
