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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Neurosci Res. 2019 Jul 11;155:56–62. doi: 10.1016/j.neures.2019.07.003

Figure 2. Repeated MDPV exposure affects dopamine-related gene expression in the NAc, VTA and PFC regions of rat’s brain.

Figure 2.

qRT-PCR quantification of the mRNA levels for DRD1 (A), DRD2 (B), DAT1 (C) and VMAT2 (D) genes in brain tissue obtained from rats treated with MDPV (1 mg/kg) 3 times/day for 10 consecutive days (brains extracted 120 min after last MDPV injection). Gene expression level in control group was set as 1. Data are presented as fold-change in gene expression normalized to GAPDH, represented as ±SEM. N=4–6. *p < 0.05 or **p < 0.01 versus saline control (MDPV 0 mg/kg).