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. 2013 Mar 17;16(2):437–468. doi: 10.1016/j.cvex.2013.02.002

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Copyright © 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 2 — Clinical appearance of rabbits with myxomatosis. (A) Acute myxomatosis caused by virulent myxoma virus. Skin lesions are present on the nose (solid arrowhead). The base of the ear is swollen (open arrowhead) and the eyes are closed with mucopurulent conjunctivitis. (B) Rabbit infected with attenuated strain of myxoma virus. The eyelid margins are red and swollen and serous discharge is present. Swelling is noted around the face and nose (arrowhead). (C) Scabbed skin lesion (approximately 2.5-cm diameter) at primary infection site. (D) Swollen testis (broad arrow); swollen genital opening (short arrow); secondary skin lesions (narrow arrow).

([A, B] From Best SM, Kerr PJ. Coevolution of host and virus: the pathogenesis of virulent and attenuated strains of myxoma virus in resistant and susceptible European rabbits. Virology 2000;267(1):36–48; with permission.)