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Antibody responses in sera of mice immunized with M2e-FP-1 and M2e-FP-2 proteins. Mice were immunized with M2e-FP-1 and M2e-FP-2 proteins, or PBS as a control, and sera were collected at the indicated time points post-immunization to detect M2e-FP-specific IgG (A), IgG1 (B), and IgG2a (C) antibodies by ELISA. The antibody titers were expressed as the endpoint dilutions that remain positively detectable, and presented as mean ± SD of 5 mice in each group.
