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A and B Survival distributions of ACAM1000 and ACAM2000, respectively, compared to negative (diluent) control and Dryvax®. Groups of 32 suckling mice (4 litters of 8 mice) were inoculated by the intracerebral route with 2.3 log10 Vero cell plaque forming units of each virus in 20 μL or with diluent. The survival distributions of ACAM vaccines and Dryvax® are significantly different (p < 0.05, long rank test).
