Table 2.
Top 10 differently expressed lncRNAs in IgAN patients as compared with healthy controls (sorted by base mean and |log2(FC)|)
| ID | Base Mean | |log2(FC)| | Padj | Protein-gene |
|---|---|---|---|---|
| Up-regulated | ||||
| G92245 | 34.51 | 3.53 | 0.016 | MED13L |
| ENSG00000234793.1_3 | 21.57 | 5.33 | 0.042 | DTYMK |
| G287980 | 14.96 | 4.89 | 0.033 | C4orf45 |
| lnc-FGL2–4 | 13.28 | 4.07 | 0.048 | FGL2 |
| lnc-RADIL-1 | 5.87 | 29.56 | < 0.001 | RADIL |
| lnc-PAXIP1–9 | 4.98 | 29.94 | < 0.001 | PAXIP1 |
| G150385 | 4.83 | 19.10 | < 0.001 | ALOX12 |
| lnc-GALNT2–1 | 3.24 | 29.44 | < 0.001 | GALNT2 |
| lnc-CSTF3–4 | 3.02 | 25.09 | < 0.001 | CSTF3 |
| G316071 | 2.88 | 26.41 | < 0.001 | IL17A |
| Down-regulated | ||||
| lnc-SPATA31E1–10 | 20.04 | 3.79 | 0.033 | AL353572.3 |
| G386979 | 19.67 | 19.69 | < 0.001 | SCAI |
| G36922 | 16.64 | 4.48 | 0.033 | PITRM1 |
| ENSG00000248266.1_4 | 11.67 | 5.80 | 0.009 | TENM3 |
| lnc-LMTK3–1 | 6.07 | 22.99 | < 0.001 | LMTK3 |
| ENSG00000268605.1_4 | 5.28 | 18.96 | < 0.001 | LIPE |
| G122951 | 4.82 | 18.62 | < 0.001 | RAB11A |
| G21551 | 4.20 | 29.20 | < 0.001 | FCGR3B |
| lnc-REV3L-2 | 3.61 | 16.36 | < 0.001 | REV3L |
| G111779 | 1.22 | 24.27 | < 0.001 | GTF2A1 |
|log2(FC)|: |log2(fold-change)|; Padj: adjusted p-value