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. 2020 Mar 31;19:43. doi: 10.1186/s12933-020-01018-3

Table 3.

Model A shows the most parsimonious Cox model, with age as the timeline, for all incident stroke events. Model B shows the addition of moderate non-proliferative diabetic retinopathy (NPDR) or worse to Model A

Baseline variable Model A Model B
Cox model, HR (95% CI) p-value Cox model, HR (95% CI) p-value
HbA1c (per 1% increase) 1.24 (1.03, 1.51) 0.027 1.21 (0.99, 1.47) 0.062
Atrial fibrillation 3.20 (1.50, 6.84) 0.003 3.50 (1.62, 7.56) 0.001
Ln (urinary albumin:creatinine)a 1.34 (1.12, 1.61) 0.002 1.30 (1.08, 1.56) 0.006
Moderate NPDR or worse 2.55 (1.19, 5.47) 0.016

aA 2.72-fold increase in urinary albumin:creatinine corresponds to an increase of 1 in ln(urinary albumin:creatinine)