Table 1.
Characteristics of Patients with Identified Respiratory Virus Infections
Characteristic | Value |
---|---|
Age, median (range) | 7.5 yr (1 mo-17.8 yr) |
Diagnosis | |
Malignant disorders | 38 |
Neuroblastoma | 12 |
Acute lymphoblastic leukemia | 6 |
Acute myeloid leukemia | 6 |
Medulloblastoma | 5 |
Hemophagocytic lymphohistiocytosis | 3 |
Non-Hodgkin lymphoma | 1 |
Hodgkin lymphoma | 1 |
MDS | 1 |
Atypical rhabdoid/teratoid tumor | 1 |
Pineoblastoma | 1 |
Ependymoblastoma | 1 |
Benign disorders | 16 |
SCID | 6 |
Severe aplastic anemia | 3 |
Wiskott Aldrich syndrome | 3 |
Thalassemia | 1 |
Sickle cell disease | 1 |
Hurler's syndrome | 1 |
Fanconi's anemia | 1 |
Type of transplant | |
Allogeneic | 32 |
HLA-identical sibling | 14 |
Family mismatch | 1 |
Unrelated donor | 17 |
Autologous | 22 |
Conditioning regimen | |
TBI + chemotherapy | 6 |
Chemotherapy alone | 43 |
No conditioning regimen | 5 |
Serotherapy | 12 |
ATG | 11 |
Alemtuzumab | 1 |
None given | 42 |
Graft type | |
Bone marrow | 25 |
Peripheral blood stem cells | 22 |
Cord blood | 7 |
Type of viral infection | |
Parainfluenza | 19 |
RSV | 15 |
Influenza A | 8 |
Influenza B | 4 |
Adenovirus | 4 |
hMPV | 2 |
Rhinovirus | 1 |
Coronavirus | 1 |
MDS indicates myelodysplastic syndrome; TBI, total body irradiation; ATG, antithymocyte globulin.