Table 2.
Details of Patients who Died from RVI after HSCT
| Diagnosis | Age at HSCT | Conditioning Regimen | Stem Cell | Respiratory Viruses | Interval, HSCT to Infection | Cause of Death |
|---|---|---|---|---|---|---|
| Severe aplastic anemia | 11 yr | Fludarabine/cyclophosphamide/ATG | Unrelated cord 5/6 | Adenovirus | 98 d | Pneumonitis, ARDS |
| Neuroblastoma, stage 4 | 18 mo | Carboplatin/etoposide/melphalan | Autologous | Adenovirus | 21 d | Pneumonitis, ARDS |
| SCID | 2 mo | Busulfan/cyclophosphamide | Matched sibling BM | RSV | 11 d | Pneumonitis, ARDS |
| Relapsed AML | 2 yr | Busulfan/cyclophosphamide | Matched sibling BM | Parainfluenza type 1 | 19 d | Pneumonitis, ARDS, pulmonary hypertension |
| Wiskott-Aldrich syndrome | 1 yr | Busulfan/cyclophosphamide/ATG | Unrelated cord 6/6 | Parainfluenza type 3 | 24 d | Pneumonitis, ARDS, pulmonary hypertension |
AML indicates acute myeloid leukemia; BM, bone marrow.