Table 2.
Characteristics at the Time of BAL
| All Patients (n = 66) |
Established Pathogen (n = 47) |
Without Established Pathogen (n = 19) |
P | |
|---|---|---|---|---|
| ICU admission to BAL, days | 2 (1-6) | 2 (0-8) | 3 (1-6) | .76 |
| Infiltrates on chest x-ray* | .91 | |||
| Focal | 11 (17) | 7 (15) | 4 (22) | |
| Multifocal/diffuse | 45 (70) | 33 (72) | 12 (67) | |
| None | 8 (13) | 6 (13) | 2 (11) | |
| Pleural effusion | 15 (23) | 10 (22) | 5 (28) | .74 |
| Number of quadrants involved on x-ray | 3 (1-4) | 4 (1-4) | 3 (1-4) | .76 |
| Absolute neutrophil count, g/L† | 1.89 (.3-5.1) | 1.89 (.21-5.99) | 2.04 (.39-4.80) | .88 |
| Absolute lymphocyte count, g/L† | .17 (.06-0.54) | .14 (.02-0.51) | .40 (.13-0.56) | .05 |
| Immunosuppressive therapies‡ | ||||
| Prednisone > 1 mg/kg | 21 (34) | 17 (39) | 4 (24) | .37 |
| Calcineurin inhibitor | 13 (21) | 9 (21) | 4 (24) | 1.0 |
| Mycophenolate mofetil | 17 (28) | 13 (30) | 4 (24) | .76 |
| No. of immunosuppressants | 1 (1-2) | 2 (1-2) | 1 (1-2) | .79 |
| Antimicrobial therapy‡ | ||||
| Intravenous broad-spectrum antibiotic | 57 (93) | 41 (93) | 16 (94) | 1.0 |
| Trimethoprim-sulfamethoxazole | 15 (25) | 8 (19) | 7 (41) | .10 |
| Anti-mold coverage | 54 (89) | 39 (89) | 15 (88) | 1.0 |
| Antiviral therapy | 26 (43) | 18 (41) | 8 (47) | .78 |
Values are number (%) or median (interquartile range).
*
Data available for 64 patients; the remaining 2 patients had a chest CT around BAL showing infiltrates.
†
Data available for 59 patients.
‡
Data available for 61 patients.