Fig. 1.

Sequence alignment and immunoreactivity of GL. a Top and side views of the Zika envelope protein dimer (Protein Data Bank structure 5IRE) with domains I, II, and III (DI, DII, DIII) indicated above the structure in the top panel. The glycan loop and the glycan are indicated in blue and orange, respectively, and the fusion loop is indicated green. b GL sequence alignment of Asian-lineage strain of ZIKV BeH823339, the prototype Ugandan MR766 strain, and other flaviviruses. The numbers indicate the position of the amino acids in the ZIKV envelope protein reference sequence, and the red N indicates the conserved glycosylation site