Figure 2.

Effect of fiber-free diets on pulmonary responses to O₃. Male and female mice were fed either a control diet or a fiber-free diet for 3 days. Shown are (A) body weight, (B) airway responsiveness of male mice exposed to O₃ (air-exposed male mice were not examined), (C) airway responsiveness of female mice exposed to room air or O₃, (D) BAL neutrophils, (E) BAL macrophages, and (F) BAL protein. Results are mean ± SE of data from 4 (air) or 8–10 (ozone) mice per group. Data were gathered over 2 and 4 experimental days for the male and female mice, respectively. On each day, fiber-free diet–fed and control diet–fed mice were studied. *P < 0.05 compared with air, ^†P < 0.05 compared with control diet–fed mice, and ^§P < 0.05 compared with male mice. Evaluation of statistical significance was performed separately for male and female mice. N.D. = not done.