Fig. 1.

Schematic diagram of a monomer of expressed full-length SARS-CoV S glycoprotein and various soluble fragments after removal of the signal sequence (residues 1–16). TM denotes the transmembrane segment and the arrow indicates possible cleavage site at amino acid residues 758–761 (RNTR). RBD indicates the potential receptor-binding domain that is within S272–537 likely between a residue downstream from 303 and a residue upstream of 537 as suggested by this work.