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. 2020 Mar 24;26:e920642-1–e920642-11. doi: 10.12659/MSM.920642

Figure 1.

Figure 1

PIK3C3 was identified to be downregulated in esophageal squamous cell carcinoma (ESCC). (A) Volcano plot showing the dysregulated genes of GSE100942 dataset. (B, C) GEO2R and GEPIA analysis were conducted to examine the expression of PIK3C3 in normal and ESCC samples from GSE100942. (D) PIK3C3 expression was measured by quantitative real-time polymerase chain reaction (qRT-PCR) in 31 pairs of normal and ESCC tissues, *** P<0.001. (E) PIK3C3 expression of 4 ESCC cell lines (KYSE-150, TE-12, EC-109, and EC-9706) were assessed using qRT-PCR, HET1A was used as normal control group, * P<0.05. (F) Survival probability of ESCC patients with low or high PIK3C3 expression.