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. 2020 Apr 1;34(7-8):495–510. doi: 10.1101/gad.333617.119

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© 2020 El-Merahbi et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genes & Development, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

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Figure 1. — ERK3 is required for induction of lipolysis. (A,B) Relative rate of glycerol release (A) and FFA release (B) (Z-score; n = 4) from 3T3L1 cells transfected with the indicated siRNA pools. (siNTC) Nontargeting control. (C,D) FFA (C) and glycerol (D) release from stromal–vascular cell (SVC)-derived adipocytes transfected with specific siRNAs and stimulated with the β-agonist isoproterenol (Iso.) and/or the HTR2b agonist BW-723C86 as indicated (n = 3). Data are presented as average ± SEM, (***) P ≤ 0.001.