Fig. 2.
Structure alignment of individual domains of several coronavirus 3CLpros. A. Schematic overview of superimposed domains of one monomer from several coronavirus 3CLpros (PEDV 3CLpro, PDB Entry: 4XFQ; SARS-CoV 3CLpro, PDB Entry: 2H2Z; TGEV 3CLpro, PDB Entry: 1LVO; PEDV 3CLpro complex, PDB Entry: 4ZUH; HCoV 229E 3CLpro, PDB Entry; 1P9S). B. RMSD values of individual domains of the PEDV 3CLpro compared with that of four additional enzymes (computed using the PDBeFold service on the European Bioinformatics Institute website).