Fig. 3.

A structural diagram of the distribution of hydrophobic and hydrophilic interactions at the dimer interface. A. The figure was generated using the LigPlot⁺ program. The residues of interface A and interface B are colored in pink and olive green, respectively. The carbon, nitrogen, and oxygen atoms are shown as black, blue and red circles, respectively. Hydrogen bonds are shown as black dashed lines labeled with the distance between the donor and corresponding acceptor atom. Hydrophobic interactions are demonstrated by arcs with spokes radiating toward the atoms (with spokes around) or residues (shown as arcs with spokes) they contact. B. Another interacting patch at the interface that is important for dimerization.