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Anti-cytomegalovirus activity and cytotoxicity of compound 31 in human embryonic lung (Hel) cells.
| Compound | EC50a (μM) AD-169 strain | CC50b (μM) |
|---|---|---|
| 31 | 9.9 ± 1.0 | 100 |
| Ganciclovir | 8.2 ± 0.3 | >350 |
| Cidofovir | 1.0 ± 0.14 | >350 |
50% Effective concentration or compound concentration required to inhibit virus-induced cytopathicity by 50%.
50% Cytotoxic concentration or compound concentration required to reduce the viability of Hel cells by 50%.
