Table 3.

Anti-HCV activity, anti-HIV activity and cytotoxicity of synthesized compounds in cellular assays.

Compound	Anti-HCV activity: % inhibition 10 μM in Huh7 cells	Anti-HIV activity (μM)		Cytotoxicity in CC50 (μM)
	HCV	EC50	EC90	PBM	CEM	Vero
8a	80.4	70.4	>100	>100	>100	>100
8b	73.6	nd	nd	nd	nd	nd
13	76.9	>100	>100	>100	>100	>100
14	60.0	>100	>100	>100	>100	>100
21	73.9	>100	>100	58.3	41.8	86.8
23	85.9	>100	>100	93.1	81.8	87.9
24	53.8	>100	>100	>100	>100	>100
25	83.1	35.8	>100	16.0	31.6	15.6
26	95.6	31.6	>100	35.9	55.3	41.0
27	95.0	43.9	>100	5.9	16.1	10.4
28	60.6	55.2	>100	19.6	37.6	12.7
29	84.3	>100	>100	61.9	31.6	47.0
30	20.8	>100	>100	>100	68.2	86.8
31	78.1	>100	>100	73.2	57.4	87.1
32	0.2	62.3	>100	32.9	31.6	17.1
33	88.7	>100	>100	19.8	16.8	10.3
34	86.5	70.5	>100	62.4	52.9	80.6