Table 4.

Proliferation inhibition on different endothelial cell types: HMEC-1 (Human Dermal Microvascular Endothelial Cells), HMVEC (Human Microvascular Endothelial Cells) and HUVEC (Human Umbilical Vein Endothelial Cells), as well as Hel (Human embryonic lung fibroblasts). IC₅₀ values represent the concentration of compound able to inhibit proliferation by 50% (Coulter Counter cell count endpoint).

Cpd.	HMEC-1 IC50 (μM)	HMVEC IC50 (μM)	HUVEC IC50 (μM)	Hel IC50 (μM)
31	0.061 ± 0.006	<0.00128	0.067 ± 0.03	0.076 ± 0.019
32	0.0035 ± 0.0009	<0.00128	0.0049 ± 0.0022	0.0092 ± 0.0066
33	0.0045 ± 0.0003	0.0019	0.018 ± 0.006	0.017 ± 0.006
34	0.018 ± 0.015	<0.00128	0.0099 ± 0.0074	0.032 ± 0.023
37	0.061 ± 0.006	N.D	N.D	N.D