Table 1.
Interaction between GPcl and NPC1-C
| GPcl | Contactsa | NPC1-C |
|---|---|---|
| V79 | 3, 2, 4 | Y423, F504, Y506 |
| P80 | 2, 19, 1 | D501, Y506, L528 |
| T83 | 7, 9, 3 | D501, F503, Y506 |
| W86 | 11 | F503 |
| G87 | 4 | F503 |
| F88 | 3, 14 | D502, F503 |
| L111 | 2, 3 | F503, F504 |
| E112 | 3 | F504 |
| I113 | 6, 6 | F503, F504 |
| K114 | 8, 1 | Q421, D428 |
| G118 | 1 | Q421 |
| V141 | 10, 5, 4 | Y423, P424, F504 |
| S142 | 6, 16, 8, 12, 3 | Y423, P424, S425, G426, F504 |
| G143 | 6, 1, 2, 4 | Q421, Y423, G426, F504 |
| T144 | 4, 13, 2, 5, 6 | Y420, Q421, F503, F504, V505 |
| G145 | 4, 2, 1 | F503, F504, V505 |
| P146 | 3, 5, 4 | D501, D502, F503 |
| C147 | 1 | D502 |
| A152 | 2 | F503 |
| I170 | 1 | F503 |
a
Numbers represent the number of atom-to-atom contacts between the GPcl residues and the NPC1-C residues, which were analyzed by the Contact program in CCP4 suite (the distance cutoff is 4.5 Å).