Table 3.
Detected antigen | Lymphoid nodules |
Dense anodular lymphoid
tissue |
Diffuse lymphoid
tissue |
|||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
L | L | A | A | D | D | C | C | L | L | A | A | D | D | C | C | L | L | A | A | D | D | C | C | |
CD3 | 1.00 | 1.00 | 1.00 | 1.00 | 1.20 | 1.20 | 1.25 | 1.20 | 2.80 | 3.00 | 2.80 | 2.60 | 2.80 | 2.60 | 3.00 | 3.00 | 1.20 | 0.80 | 1.00 | 1.40 | 1.00 | 0.80 | 1.00 | 1.00 |
0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.75 | 0.43 | 0.40 | 0.40 | 0.00 | 0.40 | 0.49 | 0.40 | 0.49 | 0.00 | 0.00 | 0.40 | 0.40 | 0.00 | 0.49 | 0.63 | 0.40 | 0.00 | 0.00 | |
CD20 | 3.20 | 3.00 | 2.80 | 2.75 | 3.00 | 3.00 | 3.40 | 2.80 | 1.60 | 1.60 | 2.00 | 1.60 | 1.60 | 1.40 | 1.60 | 1.60 | 2.00 | 1.20 | 1.80 | 1.80 | 0.80 | 1.20 | 2.40 | 1.40 |
0.40 | 0.00 | 0.40 | 0.43 | 0.00 | 0.63 | 0.49 | 0.75 | 0.49 | 0.80 | 0.63 | 0.80 | 0.49 | 0.49 | 0.49 | 0.49 | 0.63 | 0.40 | 0.98 | 0.40 | 0.40 | 0.40 | 0.49 | 0.49 | |
CD79 | 2.80 | 2.75 | 1.00 | 1.80 | 1.50 | 1.40 | 1.80 | 1.60 | 2.00 | 1.80 | 1.60 | 2.00 | 1.25 | 1.20 | 1.20 | 1.20 | 2.20 | 1.80 | 0.40 | 1.00 | 1.25 | 0.80 | 1.00 | 0.60 |
0.40 | 0.43 | 0.63 | 0.40 | 0.87 | 1.02 | 0.98 | 1.36 | 0.00 | 0.40 | 0.49 | 0.00 | 0.43 | 0.40 | 0.40 | 0.75 | 0.75 | 0.40 | 0.49 | 0.89 | 0.43 | 0.40 | 0.63 | 0.49 | |
Iba-1 | 1.60 | 1.75 | 1.00 | 1.20 | 1.00 | 1.20 | 1.20 | 1.20 | 2.00 | 1.60 | 1.40 | 1.80 | 1.20 | 1.80 | 1.60 | 1.60 | 3.00 | 2.40 | 2.00 | 2.40 | 2.20 | 2.00 | 2.00 | 2.80 |
0.49 | 0.43 | 0.63 | 0.40 | 0.00 | 0.40 | 0.40 | 0.40 | 0.00 | 0.49 | 0.80 | 0.40 | 0.40 | 0.40 | 0.49 | 0.49 | 0.00 | 0.49 | 0.63 | 0.49 | 0.75 | 0.63 | 0.63 | 0.40 | |
CD204 | 1.00 | 1.25 | 1.00 | 1.00 | 0.80 | 0.60 | 1.00 | 0.60 | 1.40 | 1.40 | 1.20 | 1.20 | 1.20 | 0.80 | 1.00 | 1.20 | 2.20 | 1.80 | 2.00 | 2.40 | 2.20 | 2.00 | 1.60 | 2.00 |
0.00 | 0.43 | 0.00 | 0.63 | 0.40 | 0.49 | 0.00 | 0.49 | 0.49 | 0.80 | 0.40 | 0.40 | 0.40 | 0.40 | 0.00 | 0.40 | 0.40 | 0.40 | 0.00 | 0.49 | 0.75 | 0.63 | 0.49 | 0.00 | |
m/h antigen | 1.20 | 0.75 | 0.80 | 0.40 | 0.80 | 0.60 | 1.00 | 0.80 | 1.00 | 0.80 | 0.80 | 0.60 | 0.80 | 1.00 | 1.40 | 1.00 | 1.80 | 1.60 | 1.20 | 1.40 | 1.40 | 1.40 | 1.40 | 1.80 |
0.40 | 0.43 | 0.40 | 0.49 | 0.40 | 0.49 | 0.00 | 0.40 | 0.00 | 0.40 | 0.40 | 0.49 | 0.40 | 0.00 | 0.80 | 0.00 | 0.40 | 0.49 | 0.40 | 0.49 | 0.80 | 0.49 | 0.49 | 0.75 | |
HLA-DR | 2.60 | 2.75 | 2.60 | 2.20 | 2.40 | 2.60 | 2.20 | 3.00 | 2.20 | 1.60 | 2.00 | 2.00 | 1.60 | 1.80 | 1.80 | 1.80 | 1.60 | 2.00 | 2.00 | 2.20 | 1.60 | 1.60 | 2.20 | 1.40 |
0.49 | 0.43 | 0.80 | 0.98 | 0.80 | 0.80 | 0.75 | 0.00 | 0.40 | 0.49 | 0.00 | 0.00 | 0.49 | 0.40 | 0.40 | 0.40 | 0.49 | 0.63 | 0.63 | 0.40 | 0.49 | 0.49 | 0.40 | 0.49 | |
CD208 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.60 | 0.80 | 0.20 | 0.40 | 0.40 | 0.00 | 0.20 | 0.20 | 1.00 | 0.20 | 0.40 | 0.40 | 0.60 | 0.60 | 0.40 | 0.60 |
0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.49 | 0.40 | 0.40 | 0.49 | 0.49 | 0.00 | 0.40 | 0.40 | 0.00 | 0.40 | 0.80 | 0.49 | 0.49 | 0.49 | 0.49 | 0.49 | |
CD68 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.20 | 0.60 | 0.60 | 0.20 | 0.40 | 0.20 | 0.20 | 0.60 | 0.40 | 0.80 | 0.80 | 0.00 | 0.00 | 0.20 | 0.20 | 0.60 | 0.40 |
0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.40 | 0.49 | 0.49 | 0.40 | 0.49 | 0.40 | 0.40 | 0.49 | 0.49 | 0.40 | 0.40 | 0.00 | 0.00 | 0.40 | 0.40 | 0.49 | 0.49 |
Averages (upper rows) and standard deviations (lower rows) of immunopositive cells were calculated from score values (0, no positive staining cells; 1, <10%; 2, 10–50%; 3, 51–90%; 4, >90% of immunolabeled cells) for different compartments of pulmonary (white values) and mesenteric lymph nodes (grey values). Thymus tissue was only available from a low number of animals and thus not included in the table. llamas; A, alpacas; D, dromedaries; C, Bactrian camels; CD, cluster of differentiation; HLA, human leucocyte antigen; Iba-1, ionized calcium-binding adapter molecule 1; m/h antigen, myeloid/histiocyte antigen.