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. 2013 Nov 21;22(1):292–302. doi: 10.1016/j.bmc.2013.11.028

Table 2.

Inhibitory activities of compounds 7a–m against SARS CoV 3CLpro

graphic file with name fx3.jpg

Compound R2 IC50 (μM)
7a graphic file with name fx4.gif 76.74 ± 2.99
7b graphic file with name fx5.gif >100
7c graphic file with name fx6.gif >100
7d graphic file with name fx7.gif 31.71 ± 1.41
7e graphic file with name fx8.gif 32.08 ± 2.83
7f graphic file with name fx9.gif 34.91 ± 9.48
7g graphic file with name fx10.gif 10.07 ± 0.59
7h graphic file with name fx11.gif 51.33 ± 2.47
7i graphic file with name fx12.gif 4.45 ± 0.13
7j graphic file with name fx13.gif 12.66 ± 0.28
7k graphic file with name fx14.gif 1.18 ± 0.11
7l graphic file with name fx15.gif 2.25 ± 0.14
7m graphic file with name fx16.gif 4.30 ± 0.07